Select Publications

Ramírez, K., Capozzo, A.V., Lloyd, S.A., Sztein, M.B., Nataro, J.P., Pasetti, M.F. Mucosally delivered Salmonella Typhi expressing the Yersinia pestis F1 antigen elicits mucosal and systemic immunity early in life and primes the neonatal immune system for a vigorous anamnestic response to parenteral F1 boost. J Immunol. 2009 Jan 15;182(2):1211-22.

Pasetti, M.F., Ramírez, K., Resendiz-Albor, A., Ulmer, J., Barry, E.M., Levine M.M. Sindbis-virus measles DNA vaccines protect cotton rats against respiratory measles; relevance of antibodies, mucosal and systemic antibody secreting cells, memory B cells and Th1-type cytokines as correlates of immunity. J Virol. 2009 Mar;83(6):2789-94.

Pasetti, M.F., Simon, J.K, Sztein, M.B., Levine, M.M. Immunology of gut mucosal vaccines. Immunol Rev. 2011 Jan;239(1):125-48.

Ramírez, M., Wahid, R., Richardson, C., Bargatze, R., El-Kamary, S.S., Sztein, M.B., Pasetti. M.F. Intranasal vaccination with an adjuvanted Norwalk virus-like particle vaccine elicits antigen-specific B memory responses in human adult volunteers. Clinical Immunol. 2012 Aug 144(2):98-108.

Heine, S. J., Diaz-McNair, J., Andar, A.U., Drachenberg, C.B., van de Verg, L., Walker, R., Picking, W. L., Pasetti, M.F. Intradermal delivery of Shigella IpaB and IpaD Type III secretion proteins: kinetics of cell recruitment and antigen uptake, mucosal and systemic immunity and protection across serotypes.  J. Immunol 2014 2014 Feb 15;192(4):1630-40. PMCID:PMC3998105.

Shimanovich, A.A., Buskirk, A.D., Heine, S.J., Blackwelder, W.C., Wahid, R., Kotloff, K.L., Pasetti, M.F. Functional and Antigen-Specific Serum Antibody Levels as Correlates of Protection Against Shigellosis in a Controlled Human Challenge Study. Clin Vaccine Immunol. 2017 Feb 6;24(2). pii: e00412-16. doi: 10.1128/CVI.00412-16.

Noel, G., Baetz, N.W., Staab, J.F., Donowitz, M., Kovbasnjuk, O., Pasetti, M.F. *, Zachos, N.C*.. A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions. Sci Rep. 2017 Mar 27;7:45270.

Sears, K.T., Tennant, S.M., Reymann, M.K., Simon, R., Konstantopoulos, N., Blackwelder, W.C., Barry, E.M., Pasetti, M.F. Bioactive Immune Components of Anti-Diarrheagenic Enterotoxigenic Escherichia coli Hyperimmune Bovine Colostrum Products. Clin Vaccine Immunol. 2017 Aug 4;24(8).

Noel, G., Doucet, M., Nataro, J.P., Kaper, J.B., Zachos, N.C., Pasetti, M.F. Enterotoxigenic Escherichia coli is phagocytosed by macrophages underlying villus-like intestinal epithelial cells: modeling ex vivo innate immune defenses of the human gut. Gut Microbes. 2017 Oct 31:0.

Ndungo, E., Randall, A., Hazen, T.H., Kania, D.A., Trappl-Kimmons, K., Liang, X., Barry, E.M., Kotloff, K.L., Chakraborty, S., Mani, S., Rasko, D.A., Pasetti, M.F. A Novel Shigella Proteome Microarray Discriminates Targets of Human Antibody Reactivity following Oral Vaccination and Experimental Challenge. mSphere. 2018 Aug 1;3(4). pii: e00260-18. doi: 10.1128/mSphere.00260-18.

Heine, S., Franco-Mahecha, O.L., Sears, K.T., Drachenberg, C.B., van Roosmalen, M.L., Leenhouts, K., Picking, W.L., Pasetti, M.F. A Combined YopB and LcrV Subunit Vaccine Elicits Protective Immunity against Yersinia Infection in Adult and Infant Mice. J Immunol. 2019 Apr 1;202(7):2005-2016.

Ndungo, E.; Pasetti. M.F. Functional antibodies and immunological endpoints to evaluate protective immunity against Shigella. Hum Vaccin Immunother. 2019 Aug 1:1-9. doi: 10.1080/21645515.2019.1640427.